We showed that sleep reactivation boosts memory consolidation of highly rewarded experiences

Michon et al, 2019

We built a platform for real-time analysis and detection of neural activation patterns

Ciliberti & Kloosterman, 2017

We optimized neural decoding algorithms for real-time use and for application to high-density neural probes

Ciliberti et al, 2018
Hu et al, 2018
Sodkomkham et al, 2016

Publications in the last 5 years


Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings
Steinmetz et al.
Science2021 Vol. 372, Issue 6539


SHYBRID: A graphical tool for generating hybrid ground-truth spiking data for evaluating spike sorting performance
Jasper Wouters, Fabian Kloosterman, Alexander Bertrand
Neuroinformatics, volume 19, pages 141–158

A Dual Reward-Place Association Task to Study the Preferential Retention of Relevant Memories in Rats
Frédéric Michon, Jyh-Jang Sun, Chae-Young Kim, Fabian Kloosterman
Front. Behav. Neurosci., 14 May 2020

A Neural Network-Based Spike Sorting Feature Map That Resolves Spike Overlap in the Feature Space
Jasper Wouters, Fabian Kloosterman, Alexander Bertrand
IEEE Transactions on Signal Processing, 1175 – 1179, 2020

System for recording from multiple flexible polyimide neural probes in freely behaving animals
Rik Van Daal, Jyh-Jang Sun, Frederik Ceyssens, Frédéric Michon, Michael Kraft, Robert Puers, Fabian Kloosterman
J. Neural Eng. 17 016046


A data-driven regularization approach for template matching in spike sorting with high-density neural probes
Jasper Wouters, Fabian Kloosterman, Alexander Bertrand 
41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Berlin, Germany, 2019, pp. 4376-4379, 2019

Post-learning hippocampal replay selectively reinforces spatial memory for highly rewarded locations
Frédéric Michon, Jyh-Jang Sun, Chae-Young Kim, Davide Ciliberti, Fabian Kloosterman
Current Biology 29(9):1436-1444.e5

Signal-to-peak-interference ratio maximization with automatic interference weighting for threshold-based spike sorting of high-density neural probe data
Jasper Wouters, Fabian Kloosterman, Alexander Bertrand
9th International IEEE/EMBS Conference on Neural Engineering (NER), San Francisco, CA, USA. pp. 247-250, 2019


Real-time readout of large-scale unsorted neural ensemble place codes
Sile Hu, Davide Ciliberti, Andres D Grosmark, Frédéric Michon, Daoyun Ji, Hector Penagos, György Buzsáki, Matthew A Wilson, Fabian Kloosterman, Zhe Chen
Cell Reports 25 (10), 2635-2642.e5

Real-time classification of experience-related ensemble spiking patterns for closed-loop applications
Davide Ciliberti, Frédéric Michon, Fabian Kloosterman
eLife 7, e36275

Algorithm/Architecture Co-optimisation Technique for Automatic Data Reduction of Wireless Read-Out in High-Density Electrode Arrays
Yassin YH, Catthoor F, Kloosterman F, Couto J, Sun JJ, Kjeldsberg PG, Van Helleputte N
ACM Transactions on Embedded Computing Systems 17(3), 1-19

Towards online spike sorting for high-density neural probes using discriminative template matching with suppression of interfering spikes
Wouters J, Kloosterman F, Bertrand A
Journal of Neural Engineering 15 (5), 056005

Characteristics of CA1 place fields in a complex maze with multiple choice points
Tanila H, Ku S, Kloosterman F, Wilson MA
Hippocampus 28 (2), 81-96


Time Multiplexed Active Neural Probe with 1356 Parallel Recording Sites
Raducanu BC, Yazicioglu RF, Lopez CM, Ballini M, Putzeys J, Wang S, Andrei A, Rochus V, Welkenhuysen M, Van Helleputte N, Musa S, Puers R, Kloosterman F, Van Hoof C, Fiáth R, Ulbert I, Mitra S
Sensors 17 (10), 2388

Falcon: a highly flexible open-source software for closed-loop neuroscience
Ciliberti D, Kloosterman F
Journal of Neural Engineering 14 (4), 045004

Involvement of fast-spiking cells in ictal sequences during spontaneous seizures in rats with chronic temporal lobe epilepsy
Neumann AR, Raedt R, Steenland HW, Sprengers M, Bzymek K, Navratilova Z, Mesina L, Xie J, Lapointe V, Kloosterman F, Vonck K, Boon PAJM, Soltesz I, McNaughton BL, Luczak A
Brain 140 (9), 2355-2369


Integration of silicon-based neural probes and micro-drive arrays for chronic recordings of large populations of neurons in behaving animals
Michon F, Aarts A, Holzhammer T, Ruther P, Borghs G, McNaughton B, Kloosterman F
Journal of Neural Engineering 13(4):046018

Kernel density compression for real-time Bayesian encoding/decoding of unsorted hippocampal spikes
Sodkomkham D, Ciliberti D, Wilson MA, Fukui K, Moriyama K, Numao M, Kloosterman F
Knowledge-Based Systems 94:1-12

A Novel Nonparametric Approach for Neural Encoding and Decoding Models of Multimodal Receptive Fields
Agarwal R, Chen Z, Kloosterman F, Sarma SV
Neural Computation 28(7):1356-87

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