We develop new technologies and experimental approaches to reveal the neural basis of brain function and behavior. Our strategy for chronic multi-neuropixel probe recording enables us to analyze the activity of distributed neuronal populations in rodents during the acquisition and execution of memory-guided behavioral tasks and during periods of rest or sleep.
Closed loop recording
We have developed novel methods for performing real-time detection of reactivated neural activity patterns, which enables closed-loop perturbations that causally link specific activity patterns to ongoing behavioral events.
Large scale measurements
Our chronic implantation strategy for multiple neuropixels probes, in combination with next generation high-density probes developed at imec, supports simultaneous large-scale measurements of cell activity across distributed brain regions.
Kloosterman Lab 